Improvements in the quality and implementation of medical care for individuals with cystic fibrosis (CF) have resulted in a dramatic improvement in survival.Many of these strategies Fasteners have focused on the effective management of pulmonary disease which has delayed its manifestations into later years.With an increasing number of patients surviving to later years the Audio Video Lead impact of chronic inflammation and nutritional compromise on other organ systems over a lifetime are increasingly manifest.This review highlights the changing epidemiology of the ageing CF population and the complications that may ensue.